TUMOR NECROSIS FACTOR-ALFA AND INTERLEUKIN-4 IN CERBROSPINAL FLUID AND PLASMA IN DIFFERENT CLINICAL FORMS OF MULTIPLE SCLEROSIS

Tumor necrosis factor-alfa and interleukin-4 in cerbrospinal fluid and plasma in different clinical forms of multiple sclerosis

Background/Aim.Multiple sclerosis (MS) is an immunemediated central nervous system disease characterized by inflammation, demyelination and axonal degeneration.Cytokines are proven mediators of immunological process in MS.The aim of this study was to investigate whether there is a difference in the production of the tumor necrosis factor alpha (TNF

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